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3-Methyladenine DNA Glycosylase is Important for Cellular Resistance to Psoralen Interstrand Cross-links

DNA interstrand cross-links (ICLs), widely used in chemotherapy, are cytotoxic lesions because they block replication and transcription. Repair of ICLs involves proteins from different repair pathways however the precise mechanism is still not completely understood. Here, we report that the 3-methyl...

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Détails bibliographiques
Auteurs principaux: Maor-Shoshani, Ayelet, Meira, Lisiane B., Yang, Xuemei, Samson, Leona D.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583468/
https://ncbi.nlm.nih.gov/pubmed/18571479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.04.017
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