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Substrate specificity and sequence dependent activity of the Saccharomyces cerevisiae 3-methyladenine DNA glycosylase (Mag)
DNA glycosylases initiate base excision repair by first binding, then excising aberrant DNA bases. S. cerevisiae encodes a 3-methyladenine (3MeA) DNA glycosylase, Mag, that recognizes 3MeA and various other DNA lesions including 1,N(6)-ethenoadenine (εA), hypoxanthine (Hx) and abasic (AP) sites. In...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494847/ https://ncbi.nlm.nih.gov/pubmed/18472311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.03.024 |
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