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3-Methyladenine DNA Glycosylase is Important for Cellular Resistance to Psoralen Interstrand Cross-links

DNA interstrand cross-links (ICLs), widely used in chemotherapy, are cytotoxic lesions because they block replication and transcription. Repair of ICLs involves proteins from different repair pathways however the precise mechanism is still not completely understood. Here, we report that the 3-methyl...

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Detalhes bibliográficos
Main Authors: Maor-Shoshani, Ayelet, Meira, Lisiane B., Yang, Xuemei, Samson, Leona D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583468/
https://ncbi.nlm.nih.gov/pubmed/18571479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.04.017
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