DNA Replication Is Required To Elicit Cellular Responses to Psoralen-Induced DNA Interstrand Cross-Links

Following introduction of DNA interstrand cross-links (ICLs), mammalian cells display chromosome breakage or cell cycle delay with a 4N DNA content. To further understand the nature of the delay, previously described as a G(2)/M arrest, we developed a protocol to generate ICLs during specific interv...

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Autors principals: Akkari, Yassmine M. N., Bateman, Raynard L., Reifsteck, Carol A., Olson, Susan B., Grompe, Markus
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
Matèries:
DNA Dynamics and Chromosome Structure
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC86436/
https://ncbi.nlm.nih.gov/pubmed/11027296
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