Substrate specificity and sequence dependent activity of the Saccharomyces cerevisiae 3-methyladenine DNA glycosylase (Mag)

DNA glycosylases initiate base excision repair by first binding, then excising aberrant DNA bases. S. cerevisiae encodes a 3-methyladenine (3MeA) DNA glycosylase, Mag, that recognizes 3MeA and various other DNA lesions including 1,N(6)-ethenoadenine (εA), hypoxanthine (Hx) and abasic (AP) sites. In...

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Bibliographic Details
Main Authors: Lingaraju, Gondichatnahalli M., Kartalou, Maria, Meira, Lisiane B., Samson, Leona D.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494847/
https://ncbi.nlm.nih.gov/pubmed/18472311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.03.024
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