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Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1

The bimolecular interaction between corticotropin-releasing factor (CRF), a neuropeptide, and its type 1 receptor (CRFR1), a class B G-protein-coupled receptor (GPCR), is crucial for activation of the hypothalamic-pituitary-adrenal axis in response to stress, and has been a target of intense drug de...

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Autori principali: Pioszak, Augen A., Parker, Naomi R., Suino-Powell, Kelly, Xu, H. Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583312/
https://ncbi.nlm.nih.gov/pubmed/18801728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805749200
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