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Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1
The bimolecular interaction between corticotropin-releasing factor (CRF), a neuropeptide, and its type 1 receptor (CRFR1), a class B G-protein-coupled receptor (GPCR), is crucial for activation of the hypothalamic-pituitary-adrenal axis in response to stress, and has been a target of intense drug de...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583312/ https://ncbi.nlm.nih.gov/pubmed/18801728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805749200 |
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