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Synthesis and solution conformation studies of the modified nucleoside N(4), 2′-O-dimethylcytidine (m(4)Cm) and its analogues
The dimethylated ribosomal nucleoside m(4)Cm and its monomethylated analogues Cm and m(4)C were synthesized. The conformations (syn versus anti) of the three modified nucleosides and cytidine were determined by CD and 1D NOE difference spectroscopy. The ribose sugar puckers were determined by the us...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583172/ https://ncbi.nlm.nih.gov/pubmed/18805697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.09.016 |
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