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Comparison of Solution Conformations and Stabilities of Modified Helix 69 rRNA Analogues from Bacteria and Human()

The helix 69 (H69) region of the large subunit (28S) rRNA of H. sapiens contains five pseudouridine (Ψ) residues out of 19 total nucleotides, three of which are highly conserved. In this study, the effects of this abundant modified nucleotide on the structure and stability of H69 were compared with...

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Detalhes bibliográficos
Main Authors: Sumita, Minako, Jiang, Jun, SantaLucia, John, Chow, Christine S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269404/
https://ncbi.nlm.nih.gov/pubmed/21858779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.21706
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