Synthesis and biological evaluation of 2′,4′- and 3′,4′-bridged nucleoside analogues

Most nucleosides in solution typically exist in equilibrium between two major sugar pucker forms, N-type and S-type, but bridged nucleosides can be locked into one of these conformations depending on their specific structure. While many groups have researched these bridged nucleosides for the purpos...

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Main Authors: Nicolaou, K. C., Ellery, Shelby P., Rivas, Fatima, Saye, Karen, Rogers, Eric, Workinger, Tyler J., Schallenberger, Mark, Tawatao, Rommel, Montero, Ana, Hessell, Ann, Romesberg, Floyd, Carson, Dennis, Burton, Dennis
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348725/
https://ncbi.nlm.nih.gov/pubmed/21840722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.07.022
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