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GEF-H1 Mediated Control of NOD1 Dependent NF-κB Activation by Shigella Effectors

Shigella flexneri has evolved the ability to modify host cell function with intracellular active effectors to overcome the intestinal barrier. The detection of these microbial effectors and the initiation of innate immune responses are critical for rapid mucosal defense activation. The guanine nucle...

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Autors principals: Fukazawa, Atsuko, Alonso, Carmen, Kurachi, Kiyotaka, Gupta, Sonal, Lesser, Cammie F., McCormick, Beth Ann, Reinecker, Hans-Christian
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583055/
https://ncbi.nlm.nih.gov/pubmed/19043560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000228
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