GEF-H1 Mediated Control of NOD1 Dependent NF-κB Activation by Shigella Effectors

Shigella flexneri has evolved the ability to modify host cell function with intracellular active effectors to overcome the intestinal barrier. The detection of these microbial effectors and the initiation of innate immune responses are critical for rapid mucosal defense activation. The guanine nucle...

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Detalhes bibliográficos
Main Authors: Fukazawa, Atsuko, Alonso, Carmen, Kurachi, Kiyotaka, Gupta, Sonal, Lesser, Cammie F., McCormick, Beth Ann, Reinecker, Hans-Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583055/
https://ncbi.nlm.nih.gov/pubmed/19043560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000228
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