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Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis

The establishment of apical–basal polarity within a single cell and throughout a growing tissue is a key feature of epithelial morphogenesis. To examine the underlying mechanisms, the human intestinal epithelial cell line Caco-2 was grown in a three-dimensional matrix to generate a cystlike structur...

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Detalles Bibliográficos
Autores principales: Jaffe, Aron B., Kaji, Noriko, Durgan, Joanne, Hall, Alan
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582895/
https://ncbi.nlm.nih.gov/pubmed/19001128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200807121
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