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Par6B and Atypical PKC Regulate Mitotic Spindle Orientation during Epithelial Morphogenesis
Cdc42 plays an evolutionarily conserved role in promoting cell polarity and is indispensable during epithelial morphogenesis. To further investigate the role of Cdc42, we have used a three-dimensional matrigel model, in which single Caco-2 cells develop to form polarized cysts. Using this system, we...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069449/ https://ncbi.nlm.nih.gov/pubmed/21300793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.174235 |
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