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Par6B and Atypical PKC Regulate Mitotic Spindle Orientation during Epithelial Morphogenesis

Cdc42 plays an evolutionarily conserved role in promoting cell polarity and is indispensable during epithelial morphogenesis. To further investigate the role of Cdc42, we have used a three-dimensional matrigel model, in which single Caco-2 cells develop to form polarized cysts. Using this system, we...

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Bibliografiska uppgifter
Huvudupphovsmän: Durgan, Joanne, Kaji, Noriko, Jin, Dan, Hall, Alan
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069449/
https://ncbi.nlm.nih.gov/pubmed/21300793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.174235
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