Wtip and Vangl2 are required for mitotic spindle orientation and cloaca morphogenesis

Defects in cilia and basal bodies function are linked to ciliopathies, which result in kidney cyst formation. Recently, cell division defects have been observed in cystic kidneys, but the underlying mechanisms of such defects remain unclear. Wtip is an LIM domain protein of the Ajuba/Zyxin family, b...

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Main Authors: Bubenshchikova, Ekaterina, Ichimura, Koichiro, Fukuyo, Yayoi, Powell, Rebecca, Hsu, Chaonan, Morrical, Stephen O., Sedor, John R., Sakai, Tatsuo, Obara, Tomoko
Format: Artigo
Language:Inglês
Published: The Company of Biologists 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509438/
https://ncbi.nlm.nih.gov/pubmed/23213452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20121016
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