Cardiolipin provides an essential activating platform for caspase-8 on mitochondria

Cardiolipin is a mitochondria-specific phospholipid known to be intimately involved with apoptosis. However, the lack of appropriate cellular models to date restricted analysis of its role in cell death. The maturation of cardiolipin requires the transacylase tafazzin, which is mutated in the human...

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Detaylı Bibliyografya
Asıl Yazarlar: Gonzalvez, Francois, Schug, Zachary T., Houtkooper, Riekelt H., MacKenzie, Elaine D., Brooks, David G., Wanders, Ronald J.A., Petit, Patrice X., Vaz, Frédéric M., Gottlieb, Eyal
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2008
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582890/
https://ncbi.nlm.nih.gov/pubmed/19001123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200803129
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