Cardiolipin provides an essential activating platform for caspase-8 on mitochondria

Cardiolipin is a mitochondria-specific phospholipid known to be intimately involved with apoptosis. However, the lack of appropriate cellular models to date restricted analysis of its role in cell death. The maturation of cardiolipin requires the transacylase tafazzin, which is mutated in the human...

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Détails bibliographiques
Auteurs principaux: Gonzalvez, Francois, Schug, Zachary T., Houtkooper, Riekelt H., MacKenzie, Elaine D., Brooks, David G., Wanders, Ronald J.A., Petit, Patrice X., Vaz, Frédéric M., Gottlieb, Eyal
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2008
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582890/
https://ncbi.nlm.nih.gov/pubmed/19001123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200803129
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