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Cardiolipin provides an essential activating platform for caspase-8 on mitochondria
Cardiolipin is a mitochondria-specific phospholipid known to be intimately involved with apoptosis. However, the lack of appropriate cellular models to date restricted analysis of its role in cell death. The maturation of cardiolipin requires the transacylase tafazzin, which is mutated in the human...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2582890/ https://ncbi.nlm.nih.gov/pubmed/19001123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200803129 |
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