RhoA–ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells

The active vitamin D metabolite 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) inhibits proliferation and promotes differentiation of colon cancer cells through the activation of vitamin D receptor (VDR), a transcription factor of the nuclear receptor superfamily. Additionally, 1,25(OH)(2)D(3) has sev...

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Detalhes bibliográficos
Main Authors: Ordóñez-Morán, Paloma, Larriba, María Jesús, Pálmer, Héctor G., Valero, Ruth A., Barbáchano, Antonio, Duñach, Mireia, de Herreros, Antonio García, Villalobos, Carlos, Berciano, María Teresa, Lafarga, Miguel, Muñoz, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582889/
https://ncbi.nlm.nih.gov/pubmed/19015318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200803020
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