Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells

Studies of RNA interference (RNAi) provide evidence that in addition to the well-characterized cytoplasmic mechanisms, nuclear mechanisms also exist. The mechanism by which the nuclear RNA-induced silencing complex (RISC) is formed in mammalian cells, as well as the relationship between the RNA sile...

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Autores principales: Ohrt, Thomas, Mütze, Jörg, Staroske, Wolfgang, Weinmann, Lasse, Höck, Julia, Crell, Karin, Meister, Gunter, Schwille, Petra
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582625/
https://ncbi.nlm.nih.gov/pubmed/18842624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn693
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