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Mixed Effects Models for Quantitative Trait Loci Mapping With Inbred Strains
Fixed effects models have dominated the statistical analysis of genetic crosses between inbred strains. In spite of their popularity, the traditional models ignore polygenic background and must be tailored to each specific cross. We reexamine the role of random effect models in gene mapping with inb...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581972/ https://ncbi.nlm.nih.gov/pubmed/18791243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.091058 |
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