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Mixed Effects Models for Quantitative Trait Loci Mapping With Inbred Strains
Fixed effects models have dominated the statistical analysis of genetic crosses between inbred strains. In spite of their popularity, the traditional models ignore polygenic background and must be tailored to each specific cross. We reexamine the role of random effect models in gene mapping with inb...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Genetics Society of America
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581972/ https://ncbi.nlm.nih.gov/pubmed/18791243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.091058 |
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