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Mixed Effects Models for Quantitative Trait Loci Mapping With Inbred Strains

Fixed effects models have dominated the statistical analysis of genetic crosses between inbred strains. In spite of their popularity, the traditional models ignore polygenic background and must be tailored to each specific cross. We reexamine the role of random effect models in gene mapping with inb...

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Bibliografiska uppgifter
Huvudupphovsmän: Bauman, Lara E., Sinsheimer, Janet S., Sobel, Eric M., Lange, Kenneth
Materialtyp: Artigo
Språk:Inglês
Publicerad: Genetics Society of America 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581972/
https://ncbi.nlm.nih.gov/pubmed/18791243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.091058
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