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Quantitative Trait Loci Association Mapping by Imputation of Strain Origins in Multifounder Crosses

Although mapping quantitative traits in inbred strains is simpler than mapping the analogous traits in humans, classical inbred crosses suffer from reduced genetic diversity compared to experimental designs involving outbred animal populations. Multiple crosses, for example the Complex Trait Consort...

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Detalhes bibliográficos
Main Authors: Zhou, Jin J., Ghazalpour, Anatole, Sobel, Eric M., Sinsheimer, Janet S., Lange, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276647/
https://ncbi.nlm.nih.gov/pubmed/22143921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.135095
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