Mapping of Quantitative Trait Loci with Knockout/Congenic Strains

Recently we have explored the use of knockout/congenic mouse strains for isolating and mapping quantitative trait loci (QTLs). Because most knockout strains have been bred to be B6.129 congenic strains, they can be used to test for QTLs in the targeted chromosomal area as long as there is a genetic...

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Detalhes bibliográficos

Publicado no:	Genome Res
Principais autores:	Bolivar, Valerie J., Cook, Melloni N., Flaherty, Lorraine
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2001
Assuntos:	Methods
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311091/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11544198/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.194001
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