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Mapping of Quantitative Trait Loci with Knockout/Congenic Strains

Recently we have explored the use of knockout/congenic mouse strains for isolating and mapping quantitative trait loci (QTLs). Because most knockout strains have been bred to be B6.129 congenic strains, they can be used to test for QTLs in the targeted chromosomal area as long as there is a genetic...

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Dades bibliogràfiques
Publicat a:Genome Res
Autors principals: Bolivar, Valerie J., Cook, Melloni N., Flaherty, Lorraine
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311091/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11544198/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.194001
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