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Active Roles for IKKα and IKKβ in NF-κB-mediated Chemoresistance to Doxorubicin

Chemotherapy agents have been shown to induce the transcription factor NF-κB and subsequent chemoresistance in fibrosarcomas and other cancers. The mechanism of NF-κB-mediated chemoresistance remains unclear, with a previous report suggesting that doxorubicin induces this response independent of the...

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Detalhes bibliográficos
Main Authors: Bednarski, Brian K., Ding, Xiaoyu, Coombe, Kavita, Baldwin, Albert S., Kim, Hong J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581801/
https://ncbi.nlm.nih.gov/pubmed/18644995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0321
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