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Structure of the ligand-binding domain of rat VDR in complex with the nonsecosteroidal vitamin D(3) analogue YR301
Vitamin D receptor (VDR) is a ligand-inducible hormone receptor that mediates 1α,25(OH)(2)D(3) action, regulating calcium and phosphate metabolism, induces potent cell differentiation activity and has immunosuppressive effects. Analogues of 1α,25(OH)(2)D(3) have been used clinically for some years....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581693/ https://ncbi.nlm.nih.gov/pubmed/18997319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108026754 |
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