Structure of the ligand-binding domain of rat VDR in complex with the nonsecosteroidal vitamin D(3) analogue YR301

Vitamin D receptor (VDR) is a ligand-inducible hormone receptor that mediates 1α,25(OH)(2)D(3) action, regulating calcium and phosphate metabolism, induces potent cell differentiation activity and has immunosuppressive effects. Analogues of 1α,25(OH)(2)D(3) have been used clinically for some years....

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Hlavní autoři: Kakuda, Shinji, Okada, Kazuhisa, Eguchi, Hiroshi, Takenouchi, Kazuya, Hakamata, Wataru, Kurihara, Masaaki, Takimoto-Kamimura, Midori
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2008
Témata:
Protein Structure Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581693/
https://ncbi.nlm.nih.gov/pubmed/18997319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108026754
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