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A SQSTM1/p62 mutation linked to Paget’s disease increases the osteoclastogenic potential of the bone microenvironment

Paget’s disease of bone (PDB) is the second most common bone disease and is characterized by focal bone lesions which contain large numbers of abnormal osteoclasts (OCLs) and very active normal osteoblasts in a highly osteoclastogenic marrow microenvironment. The etiology of PDB is not well understo...

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Main Authors: Hiruma, Yuko, Kurihara, Noriyoshi, Subler, Mark A., Zhou, Hua, Boykin, Christina S., Zhang, Heju, Ishizuka, Seiichi, Dempster, David W., Roodman, G. David, Windle, Jolene J.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581430/
https://ncbi.nlm.nih.gov/pubmed/18765443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn266
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