Načítá se...
Do Enthalpy and Entropy Distinguish First in Class From Best in Class?
A drug molecule should bind to its target with high affinity and selectivity. Since the binding affinity is a combined function of the binding enthalpy and the binding entropy, extremely high affinity requires that both terms contribute favorably to binding. The binding enthalpy, however, is notorio...
Uloženo v:
| Hlavní autor: | |
|---|---|
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581116/ https://ncbi.nlm.nih.gov/pubmed/18703160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis2008.07.005 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|