Nuclear structure in normal and Bloom syndrome cells

Bloom syndrome (BS) is a rare cancer-predisposing disorder in which the cells of affected persons have a high frequency of somatic mutation and genomic instability. BLM, the protein altered in BS, is a RecQ DNA helicase. This report shows that BLM is found in the nucleus of normal human cells in the...

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Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Yankiwski, Victor, Marciniak, Robert A., Guarente, Leonard, Neff, Norma F.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 2000
Pynciau:	Biological Sciences
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25808/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10779560/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.090525897
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