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Nuclear structure in normal and Bloom syndrome cells

Bloom syndrome (BS) is a rare cancer-predisposing disorder in which the cells of affected persons have a high frequency of somatic mutation and genomic instability. BLM, the protein altered in BS, is a RecQ DNA helicase. This report shows that BLM is found in the nucleus of normal human cells in the...

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Detalhes bibliográficos
Main Authors: Yankiwski, Victor, Marciniak, Robert A., Guarente, Leonard, Neff, Norma F.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25808/
https://ncbi.nlm.nih.gov/pubmed/10779560
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