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Interferon-γ and interleukin-4 reciprocally regulate CD8 expression in CD8(+) T cells
The CD8 co-receptor can modulate CD8(+) T cell function through its contributions to T cell receptor (TCR) binding and signaling. Here we show that IFN-γ and IL-4 exert opposing effects on the expression of CD8α mRNA and surface CD8 protein during CD8(+) T cell activation. IL-4 caused down-regulatio...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2580749/ https://ncbi.nlm.nih.gov/pubmed/18988742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809549105 |
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