Disruption of the NHR4 domain structure in AML1-ETO abrogates SON binding and promotes leukemogenesis

AML1-ETO is generated from t(8;21)(q22;q22), which is a common form of chromosomal translocation associated with development of acute myeloid leukemia (AML). Although full-length AML1-ETO alone fails to promote leukemia because of its detrimental effects on cell proliferation, an alternatively splic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ahn, Eun-Young, Yan, Ming, Malakhova, Oxana A., Lo, Miao-Chia, Boyapati, Anita, Ommen, Hans Beier, Hines, Robert, Hokland, Peter, Zhang, Dong-Er
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579385/
https://ncbi.nlm.nih.gov/pubmed/18952841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802696105
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados