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TAF1 plays a critical role in AML1-ETO driven leukemogenesis
AML1-ETO (AE) is a fusion transcription factor, generated by the t(8;21) translocation, that functions as a leukemia promoting oncogene. Here, we demonstrate that TATA-Box Binding Protein Associated Factor 1 (TAF1) associates with K43 acetylated AE and this association plays a pivotal role in the pr...
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| Udgivet i: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6820555/ https://ncbi.nlm.nih.gov/pubmed/31664040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12735-z |
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