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Prognostic implication of p27(Kip1), Skp2 and Cks1 expression in renal cell carcinoma: a tissue microarray study

BACKGROUND: p27(Kip1 )plays a major role as a negative regulator of the cell cycle. The regulation of p27(Kip1 )degradation is mediated by its specific ubiquitin ligase subunits S-phase kinase protein (Skp) 2 and cyclin-dependent kinase subunit (Cks) 1. However, little is known regarding the prognos...

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Autores principales: Liu, Zheng, Fu, Qiang, Lv, Jiaju, Wang, Facheng, Ding, Kejia
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579281/
https://ncbi.nlm.nih.gov/pubmed/18922157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-27-51
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