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Prognostic implication of p27(Kip1), Skp2 and Cks1 expression in renal cell carcinoma: a tissue microarray study
BACKGROUND: p27(Kip1 )plays a major role as a negative regulator of the cell cycle. The regulation of p27(Kip1 )degradation is mediated by its specific ubiquitin ligase subunits S-phase kinase protein (Skp) 2 and cyclin-dependent kinase subunit (Cks) 1. However, little is known regarding the prognos...
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Glavni autori: | , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
BioMed Central
2008
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2579281/ https://ncbi.nlm.nih.gov/pubmed/18922157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-27-51 |
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