Misactivated amino acids translocate at similar rates across surface of a tRNA synthetase
Certain aminoacyl-tRNA synthetases have a second active site that destroys (by hydrolysis) errors of amino acid activation. For example, isoleucyl-tRNA synthetase misactivates valine (to produce valyl adenylate or Val-tRNA(Ile)) at its active site. The misactivated amino acid is then translocated to...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25791/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10792042/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.090102197 |
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