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Misactivated amino acids translocate at similar rates across surface of a tRNA synthetase

Certain aminoacyl-tRNA synthetases have a second active site that destroys (by hydrolysis) errors of amino acid activation. For example, isoleucyl-tRNA synthetase misactivates valine (to produce valyl adenylate or Val-tRNA(Ile)) at its active site. The misactivated amino acid is then translocated to...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Nomanbhoy, Tyzoon K., Schimmel, Paul R.
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 2000
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25791/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10792042/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.090102197
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