Exonucleolysis is required for nuclear mRNA quality control in yeast THO mutants

Production of aberrant messenger ribonucleoprotein particles (mRNPs) is subject to quality control (QC). In yeast strains carrying mutations of the THO complex, transcription induction triggers a number of interconnected QC phenotypes: (1) rapid degradation of several mRNAs; (2) retention of a fract...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Assenholt, Jannie, Mouaikel, John, Andersen, Kasper R., Brodersen, Ditlev E., Libri, Domenico, Jensen, Torben Heick
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2008
Soggetti:
Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2578857/
https://ncbi.nlm.nih.gov/pubmed/18824516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1108008
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi