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Dissecting mechanisms of nuclear mRNA surveillance in THO/sub2 complex mutants
The nuclear exosome is involved in numerous RNA metabolic processes. Exosome degradation of rRNA, snoRNA, snRNA and tRNA in Saccharomyces cerevisiae is activated by TRAMP complexes, containing either the Trf4p or Trf5p poly(A) polymerase. These enzymes are presumed to facilitate exosome access by ap...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1864968/ https://ncbi.nlm.nih.gov/pubmed/17410208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601669 |
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