Exonucleolysis is required for nuclear mRNA quality control in yeast THO mutants

Production of aberrant messenger ribonucleoprotein particles (mRNPs) is subject to quality control (QC). In yeast strains carrying mutations of the THO complex, transcription induction triggers a number of interconnected QC phenotypes: (1) rapid degradation of several mRNAs; (2) retention of a fract...

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Detaylı Bibliyografya
Asıl Yazarlar: Assenholt, Jannie, Mouaikel, John, Andersen, Kasper R., Brodersen, Ditlev E., Libri, Domenico, Jensen, Torben Heick
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2008
Konular:
Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2578857/
https://ncbi.nlm.nih.gov/pubmed/18824516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1108008
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