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Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain

The multisubunit eukaryotic exosome is an essential RNA processing and degradation machine. In its nuclear form, the exosome associates with the auxiliary factor Rrp6p, which participates in both RNA processing and degradation reactions. The crystal structure of Saccharomyces cerevisiae Rrp6p displa...

詳細記述

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書誌詳細
主要な著者: Midtgaard, Søren F., Assenholt, Jannie, Jonstrup, Anette Thyssen, Van, Lan B., Jensen, Torben Heick, Brodersen, Ditlev E.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2131688/
https://ncbi.nlm.nih.gov/pubmed/16882719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604731103
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