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Targeting the nuclear RNA exosome: Poly(A) binding proteins enter the stage

Centrally positioned in nuclear RNA metabolism, the exosome deals with virtually all transcript types. This 3′–5′ exo- and endo-nucleolytic degradation machine is guided to its RNA targets by adaptor proteins that enable substrate recognition. Recently, the discovery of the ‘Poly(A) tail exosome tar...

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Bibliografiske detaljer
Udgivet i:RNA Biol
Main Authors: Meola, Nicola, Jensen, Torben Heick
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546719/
https://ncbi.nlm.nih.gov/pubmed/28421898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2017.1312227
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