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Extensive degradation of RNA precursors by the exosome in wild type cells

The exosome is a complex involved in the maturation of rRNA and sn-snoRNA, the degradation of short lived non-coding RNAs and in the quality control of RNAs produced in mutants. It contains two catalytic subunits, Rrp6p and Dis3p, whose specific functions are not fully understood. We analyzed the tr...

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Detalhes bibliográficos
Main Authors: Gudipati, Rajani Kanth, Xu, Zhenyu, Lebreton, Alice, Séraphin, Bertrand, Steinmetz, Lars M., Jacquier, Alain, Libri, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496076/
https://ncbi.nlm.nih.gov/pubmed/23000176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.08.018
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