Structural and functional evidence that Nck interaction with CD3ε regulates T cell receptor activity

Recruitment of signaling molecules to the cytoplasmic domains of the CD3 subunits of the T cell receptor (TCR) is crucial for early T cell activation. These transient associations either do or do not require tyrosine phosphorylation of CD3 immune tyrosine activation motifs (ITAMs). Here we show that...

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Bibliografski detalji
Glavni autori: Takeuchi, Koh, Yang, Hailin, Ng, Elise, Park, Sungh-youk, Sun, Zhen-Yu J., Reinherz, Ellis L., Wagner, Gerhard
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577852/
https://ncbi.nlm.nih.gov/pubmed/18555270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.05.037
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