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TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

The role of tumor necrosis factor (TNF) as an immune mediator has long been appreciated but its function in the brain is still unclear. TNF receptor 1 (TNFR1) is expressed in most cell types, and can be activated by binding of either soluble TNF (solTNF) or transmembrane TNF (tmTNF), with a preferen...

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Detalhes bibliográficos
Main Authors: McCoy, Melissa K, Tansey, Malú G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577641/
https://ncbi.nlm.nih.gov/pubmed/18925972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-5-45
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