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Regulation of Microglia Effector Functions by Tumor Necrosis Factor (TNF) Signaling

The exact biological role of the cytokine Tumor Necrosis Factor (TNF) in the central nervous system (CNS) is not well understood; but overproduction of TNF by activated microglia has been implicated in neuronal death, suggesting that TNF inhibition in the CNS may be a viable neuroprotective strategy...

詳細記述

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書誌詳細
主要な著者: Harms, Ashley S., Lee, Jae-Kyung, Nguyen, Thi A., Chang, Jianjun, Ruhn, Kelly M., Treviño, Isaac, Tansey, Malú G.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232308/
https://ncbi.nlm.nih.gov/pubmed/21989628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21254
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