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The kinetics of Ca(2+)-dependent switching in a calmodulin-IQ domain complex

We have performed a kinetic analysis of Ca(2+)-dependent switching in the complex between calmodulin (CaM) and the IQ domain from neuromodulin, and have developed detailed kinetic models for this process. Our results indicate that the affinity of the C-ter Ca(2+)-binding sites in bound CaM is reduce...

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Hlavní autoři: Black, DJ, Selfridge, J. Eva, Persechini, Anthony
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577580/
https://ncbi.nlm.nih.gov/pubmed/17958378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700774s
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